96-Channel Ultra High Throughput Octet System : Octet RH96

96-Channel Ultra High Throughput Octet® System

Analyze up to 96 samples simultaneously - Perform your quantitation or binding experiments with unmatched speed. Quantitate a full 96-well plate of IgGs in two minutes.
Perform a 32 x 32 epitope binning campaign in less than eight hours - Use in-tandem, sandwich, or pre-mix assay formats to perform epitope binning. Analyze samples directly from supernatants or lysates. Complete a 32 x 32 epitope binning assay in less than eight hours.
Streamline workflows with automation – Automation-ready and robot-compatible for microplate and biosensor tray loading for extending walk-away times and reducing operator input.
From IgG titer to epitope binning, the Octet® RH96 instrument offers label-free molecular interaction analysts with state-of-the-art high throughput platforms that facilitate the rapid characterization and development of biologics drug molecules.

Simultaneously reads 8, 16, 32, 48 or 96 wells
The Octet® RH96 instrument read head provides design flexibility that allows users to analyze, 8, 16, 32, 48, or 96 samples at a time allowing for customized throughput up to 96 samples.

Full plate off-rate ranking in minutes, not hours
The Dip and Read assay format allows off-rate analysis of clones to be performed rapidly, even in crude samples using ready-to-use biosensors off the shelf.

96-well plate quantitation in as little as two minutes
IgG titer determination of a full 96-well plate can be completed in two minutes. In addition, sample plate compartment is compatible with 384-well plates allowing for greater sample throughput.

32 x 32 epitope binning in less than eight hours
With the Octet® RH96 system, epitope binning can be completed in record time, where a 32 x 32 antibody matrix can be analyzed in less than eight hours. A powerful dedicated epitope binning analysis software enables easy visualization and analysis of large data sets.

Microfluidics-free Dip and Read format reduces assay time and maintenance cost
The Octet® RH96 system utilizes Dip-and-Read technology where biosensors dip into samples housed in microplates. With no fluidics involved, Octet® systems have more uptime and lower operational costs

Applications

ELISA Conversion
ELISAs are known for having variability in results, susceptibility to human error, and slow times-to-results. High throughput Octet® systems are designed to overcome those limitations. Convert your ELISA assay into an Octet® assay.

Epitope Binning
The epitope binning process identifies and arranges antibody candidates that bind similar epitope regions to an antigen into bins. Octet® epitope binning assays rely on testing the sequential binding ability of two antibodies to an antigen. Assay speed, throughput, exceptional reproducibility, and dedicated software tools make Octet® platforms ideal for analyzing large antibody libraries.

protein contaminant diagram
Protein Contaminant Testing
Protein contaminants are a major hurdle to overcome during the production of biopharmaceuticals. The Octet® platform's rapid high throughput protein analysis combined with the anti-CHO HCP and Residual Protein A kits provide biologics developers with a fast and easy-to-use assay for contaminant testing.