Thermo Fisher Scientific SLC6A8 Polyclonal Antibody
SLC6A8 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunocytochemistry에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며, 고순도의 Affinity chromatography로 정제되었습니다. PBS/glycerol buffer에 보관되며 연구용으로 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SLC6A8 (Accession P48029), corresponding to amino acid residues R582–E632 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2854414 |
Product Specific Information
This antibody detects endogenous levels of total SLC6A8.
Target Information
SLC6A8 (solute carrier family 6 member 8), also known as CT1 (creatine transporter 1), CRT, or CRTR, is a 635 amino acid multi-pass plasma membrane protein that belongs to the sodium/neurotransmitter (SNF) family. It is expressed in various tissues including kidney, skeletal muscle, heart, brain, prostate, testis, and colon.
SLC6A8 functions to transport creatine into and out of cells, particularly in brain and muscle tissue. Creatine is an organic acid essential for energy supply in muscle and nerve function.
Defects in the SLC6A8 gene cause cerebral creatine deficiency and X-linked creatine deficiency syndrome, characterized by facial anomalies, seizures, and intellectual disability. Multiple isoforms exist due to alternative splicing events.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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