Thermo Fisher Scientific SLC9A7 Polyclonal Antibody
SLC9A7 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Western Blot 및 Immunocytochemistry에 적합합니다. 고순도 Affinity Chromatography 정제, PBS/glycerol buffer 보존, -20°C 보관 조건으로 안정적입니다.
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Thermo Fisher Scientific SLC9A7 Polyclonal Antibody
Applications and Tested Dilutions
- Western Blot (WB): 1:500–1:1,000
- Immunocytochemistry (ICC/IF): 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SLC9A7 (Accession Q96T83), corresponding to amino acid residues L535–A585 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2854416 |
Product Specific Information
This antibody detects endogenous levels of total SLC9A7.
Target Information
Na⁺/H⁺ exchangers (NHE) are plasma membrane intrinsic proteins mediating exchange of Na⁺ and H⁺ ions across various tissues. They play a vital role in:
- Regulation of intracellular pH (pHi)
- Trans-cellular Na⁺ absorption
- Cell volume regulation
- Potential involvement in cell proliferation
These functions are associated with pathophysiological states such as hypertension, organ growth and hypertrophy, cancer regression, and renal intestinal disorders.
At least seven NHE isoforms (NHE1–7) have been cloned, sharing similar primary structures with 10–12 predicted transmembrane domains.
NHE7 (human, 725 aa, chromosome Xp11.4) is ubiquitously expressed and mainly localized to the trans-Golgi network, mediating Na⁺ or K⁺ influx in exchange for H⁺. It shares ~70% similarity with NHE6 and ~25% with other NHE isoforms.
For Research Use Only.
Not for use in diagnostic procedures or resale without authorization.
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