Thermo Fisher Scientific ZNF408/PRDM17 (Transcription Factor) Monoclonal Antibody (PCRP-ZNF408-1E5)
ZNF408/PRDM17 전사인자에 특이적인 Thermo Fisher Scientific의 단클론 항체입니다. Western blot, 유세포분석, 펩타이드 어레이 등에 적합하며, 인간 시료 반응성을 가집니다. 단백질 A/G 정제, 액상 형태로 제공되며 4°C에서 보관합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PCRP-ZNF408-1E5 |
| Immunogen | Recombinant full-length human ZNF408 protein (amino acids 1–720) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Zinc-finger proteins contain DNA-binding domains and perform diverse functions, including transcriptional activation or repression. Most zinc-finger proteins have a Kruppel-type DNA-binding domain and a KRAB domain that interacts with KAP1 to recruit histone-modifying proteins.
ZNF408 (also known as PRDM17) is a member of the Kruppel C2H2-type zinc-finger protein family. It is a 720-amino-acid nuclear protein containing 10 C2H2-type zinc fingers. The ZNF408 gene maps to human chromosome 11, which contains over 1,400 genes and represents nearly 4% of the human genome. Mutations in genes on chromosome 11 are associated with disorders such as Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema, and Smith-Lemli-Opitz syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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