Thermo Fisher Scientific DCP1A Recombinant Rabbit Monoclonal Antibody (23GB5150)
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카탈로그 번호 | CAS 번호 | 설명 | 상태 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
MA553854 | - | Thermo Fisher Scientific MA553854 DCP1A Recombinant Rabbit Monoclonal Antibody (23GB5150) 100 uL pk | 재고문의 | pk | 0원 | - | 0원 | |
MA553855 | - | Thermo Fisher Scientific MA553855 DCP1A Recombinant Rabbit Monoclonal Antibody (23GB5150) 20 uL pk | 재고문의 | pk | 0원 | - | 0원 |
다른 상품 둘러보기
Applications
Tested Dilution
Publications
Western Blot (WB)
1:1,000-1:5,000
Flow Cytometry (Flow)
1:2,000
Product Specifications
Species Reactivity
Human, Mouse
Host/Isotype
Rabbit / IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
23GB5150
Immunogen
A synthesized peptide derived from human DCP1A (500-582AA). if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
DCP1A,
uniProtId:
Q9NPI6-1,
ncbiNodeId:
9606,
antigenRange:
500-582,
antigenLength:
582,
antigenImageFileName:
MA5-53854_DCP1A_Q9NPI6-1_Rabbit.svg,
antigenImageFileNamePDP:
MA5-53854_DCP1A_Q9NPI6-1_Rabbit_PDP.jpeg,
sortOrder:
1}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Target Information
Signal transduction of TGF-beta superfamily members is regulated by Smad proteins. In particular, Smads influence specific gene transcription by relaying signals from the cell membrane to the nucleus. Smad4 plays an essential role in TGF-beta-induced transcriptional activation wherein phosphorylated receptor-associated Smads associate with Smad4. Furthermore, SMIF (Smad4-intereacting protein) and Smad4 complex with TGF-beta and BMP4. An increase in Smad4 concentration increases the translocation of this complex to the nucleus. SMIF and Smad4 interact directly through a EVH1/WH1 domain on SMIF and a proline-rich activation domain on Smad4. Smad4 is essential to nuclear translocation of SMIF as deletion of the Smad4-interacting domain (located in the N-terminal 100 amino acids) of SMIF eliminates TGF-beta-induced nuclear translocation of SMIF. The human SMIF gene is ubiquitously expressed and encodes a protein with a relative molecular mass of 70 kDa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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