Thermo Fisher Scientific B7-H3 Recombinant Rabbit Monoclonal Antibody (23GB5035)
B7-H3(CD276) 단백질을 표적으로 하는 재조합 토끼 단클론 항체로, 인간 시료에 반응합니다. Western blot과 Flow cytometry에 최적화되어 있으며, 고순도 친화성 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:5,000
Flow Cytometry (Flow)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB5035 |
| Immunogen | A synthesized peptide derived from human CD276 (1–534AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
CD276, also known as B7-H3, is a member of the B7 family of co-stimulatory molecules. It is a type I transmembrane protein that induces proliferation of CD4+ and CD8+ T cells, enhances cytotoxic T cell generation, and selectively stimulates interferon gamma production. Expression of CD276 can be induced on dendritic cells and monocytes by inflammatory cytokines and is widely expressed in peripheral tissues including the heart, kidney, testis, and colon. In humans, CD276 exists as two isoforms resulting from gene duplication and differential splicing. CD276 has therapeutic potential for regulating cell-mediated immune responses to cancer, particularly in conjunction with anti-angiogenic therapy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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