Thermo Fisher Scientific QRFPR Polyclonal Antibody
QRFPR 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. IHC(P)에서 8 µg/mL로 검증됨. 인간, 소, 말, 돼지, 토끼 등 다양한 종에 반응. 항원 친화 크로마토그래피로 정제된 액상 형태, PBS 버퍼 및 0.1% sodium azide 함유.
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Thermo Fisher Scientific QRFPR Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) [IHC(P)]
Tested dilution: 8 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Horse, Human, Pig, Rabbit |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 20 amino acid peptide from N-Terminus of human QRFPR / GPR103 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551502 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- Human, Gorilla, Gibbon, Marmoset, Bovine, Horse, Rabbit, Pig (100%)
- Monkey, Rat, Dog, Elephant (95%)
- Mouse, Panda (90%)
Target Information
G protein-coupled receptors (GPRs) are a protein family of transmembrane receptors that transmit extracellular signals (ligand binding) into intracellular signals (G protein activation).
GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication.
All receptors have seven membrane-spanning domains, and the extracellular parts can be glycosylated. These loops contain two conserved cysteine residues forming disulfide bonds to stabilize the receptor structure.
GPR103 is a 455 amino acid protein highly expressed in the brain, retina, trigeminal ganglion, hypothalamus, and vestibular nucleus. In peripheral tissues, it is expressed in the heart, kidney, and testis. GPR103 may regulate adrenal function. A hypothalamic neuropeptide of the RFamide family (26RFa) acts as an endogenous ligand for GPR103.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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