Thermo Fisher Scientific QRFPR Polyclonal Antibody
QRFPR 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 검증됨. 인간 QRFPR C-말단 20아미노산 펩타이드로부터 제작됨. 1 mg/mL 농도의 액상 형태이며, 냉장(2–8°C) 보관 권장. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 5.2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 20 amino acid peptide from C-terminus of human QRFPR / GPR103 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 1 month. For long-term storage, store at -20°C. |
| Shipping Conditions | Wet ice |
| RRID | AB_2551501 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Gorilla (100%), Gibbon (95%), Monkey (90%), Bovine, Elephant, Horse, Pig (80%).
Target Information
G protein-coupled receptors (GPRs) are a family of transmembrane receptors that transmit extracellular signals (ligand binding) into intracellular signals (G protein activation). GPR signaling is an evolutionarily conserved mechanism in eukaryotes for sensing environmental stimuli and mediating cell-cell communication.
All receptors have seven membrane-spanning domains, and their extracellular regions may be glycosylated. Two conserved cysteine residues form disulfide bonds to stabilize the receptor structure.
GPR103 is a 455 amino acid protein highly expressed in the brain, retina, trigeminal ganglion, hypothalamus, and vestibular nucleus. In peripheral tissues, expression is limited to the heart, kidney, and testis. GPR103 may regulate adrenal function. The hypothalamic neuropeptide 26RFa acts as an endogenous ligand for GPR103.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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