Thermo Fisher Scientific QRFPR Polyclonal Antibody
Human QRFPR 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 등 다양한 연구용 응용에 적합. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 순도를 제공. PBS 완충액에 보존되며, 장기 보관 시 -20°C에서 안정적 유지.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P))
Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 20 amino acid peptide from the C-terminus cytoplasmic domain of human QRFPR / GPR103 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551500 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- Human (100%)
- Gorilla, Gibbon, Monkey, Marmoset (95%)
- Dog (85%)
- Horse, Rabbit (80%)
Target Information
G protein-coupled receptors (GPRs) are a family of transmembrane receptors that transmit extracellular signals (ligand binding) into intracellular signals (G protein activation). This signaling mechanism is used by eukaryotes to sense environmental stimuli and mediate cell-cell communication.
All GPRs have seven membrane-spanning domains; extracellular regions may be glycosylated and contain conserved cysteine residues forming disulfide bonds for structural stability.
GPR103 is a 455 amino acid protein highly expressed in the brain, retina, trigeminal ganglion, hypothalamus, and vestibular nucleus. In peripheral tissues, it is expressed in the heart, kidney, and testis, and may regulate adrenal function. The hypothalamic neuropeptide 26RFa acts as an endogenous ligand for GPR103.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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