Thermo Fisher Scientific ASL Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 0.1–0.5 µg/mL

Product Specifications

Product Specific Information

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.

Target Information

ASL encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate — an essential step in the urea cycle for detoxifying ammonia in the liver.
Mutations in this gene cause the autosomal recessive disorder argininosuccinic aciduria (argininosuccinic acid lyase deficiency).
A nontranscribed pseudogene is located on chromosome 22q.
Alternatively spliced transcript variants encoding different isoforms have been described.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.