Thermo Fisher Scientific EVC2 Polyclonal Antibody

Applications

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:20–1:50

Immunocytochemistry (ICC/IF)

• Tested Dilution: 0.25–2 µg/mL

Product Specifications

Product Specific Information

Immunogen sequence:
KRESPITHRL YGDISREVQG TSENGVIFQK CALVSGSSEA QTARIWLLVN NTKTTSSANL SELLLLDSIA GLTIWDSVGN RTSEGFQAFS KKFLQV

Highest antigen sequence identity to the following orthologs:

• Mouse: 55%
• Rat: 58%

Target Information

This gene encodes a protein that functions in bone formation and skeletal development.
Mutations in this gene, as well as in a neighboring gene that lies in a head-to-head configuration, cause Ellis-van Creveld syndrome, an autosomal recessive skeletal dysplasia also known as chondroectodermal dysplasia.
Mutations in this gene also cause acrofacial dysostosis Weyers type (Curry-Hall syndrome), characterized by limb and facial abnormalities.
Alternative splicing results in multiple transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.