Thermo Fisher Scientific MYO5B Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human MYO5B. Recombinant protein control fragment (Product #RP-98269). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MYO5B,uniProtId:Q9ULV0-1,ncbiNodeId:9606,antigenRange:1054-1148,antigenLength:1848,antigenImageFileName:PA5-59344_MYO5B_Q9ULV0-1_Rabbit.svg,antigenImageFileNamePDP:PA5-59344_MYO5B_Q9ULV0-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2644374

Product Specific Information

Immunogen sequence: NLMKKELEEE RSRYQNLVKE YSQLEQRYDN LRDEMTIIKQ TPGHRRNPSN QSSLESDSNY PSISTSEIGD TEDALQQVEE IGLEKAAMDM TVFLK

Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 89%.

Target Information

May be involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. Required in a complex with RAB11A and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Together with RAB11A participates in CFTR trafficking to the plasma membrane and TF (transferrin) recycling in nonpolarized cells. Together with RAB11A and RAB8A participates in epithelial cell polarization. Together with RAB25 regulates transcytosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.