Thermo Fisher Scientific JAKMIP2 Polyclonal Antibody
JAKMIP2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간, 생쥐, 랫트 반응성. IHC, ICC/IF, ELISA에 사용 가능. 고순도 Protein A 정제, 1 mg/mL 농도, -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human JAKMIP2/NECC1 (amino acids 21–120) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
JAKMIP2 (Janus kinase and microtubule-interacting protein 2), also known as NECC1 (neuroendocrine long coiled-coil protein 1), CTCL tumor antigen HD-CL-04, JAMIP2, or KIAA0555, is a 810-amino-acid protein of the JAKMIP family.
It localizes to the Golgi apparatus and is highly expressed in the brain, with moderate expression in thymus, spleen, and lung.
Three alternatively spliced isoforms exist. The JAKMIP2 gene maps to human chromosome 5q32 and mouse chromosome 18 B3.
Chromosome 5 contains about 181 million base pairs (≈6% of the human genome). Deletions of the p arm cause Cri du chat syndrome, while deletions of the q arm or entire chromosome 5 are linked to therapy-related acute myelogenous leukemia and myelodysplastic syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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