Thermo Fisher Scientific Fibrinogen gamma Monoclonal Antibody (4H9)
FGG 단백질을 검출하는 Mouse IgG2a 단클론 항체로, WB, IHC, ICC/IF, Flow, ELISA 등 다양한 응용에 적합. 인간 및 생쥐 시료 반응성. 비결합형 액상 형태로 1 mg/mL 농도, 안정적이며 장기 보관 가능.
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Thermo Fisher Scientific Fibrinogen gamma Monoclonal Antibody (4H9)
Applications 및 권장 희석 배율
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | - |
| Immunohistochemistry (IHC) | - | 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 | 1 publication |
| Flow Cytometry (Flow) | 1:200–1:400 | - |
| ELISA | 1:10,000 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4H9 |
| Immunogen | Purified recombinant fragment of human FGG expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11153062 |
Product Specific Information
MA5-15906 targets FGG in indirect ELISA, FACS, IF, IHC, and WB applications and shows reactivity with Human samples.
The immunogen is a purified recombinant fragment of human FGG expressed in E. coli.
MA5-15906 detects FGG, which has a predicted molecular weight of approximately 52 kDa.
Target Information
The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains.
Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin, the most abundant component of blood clots.
Various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types.
Mutations in this gene lead to disorders such as dysfibrinogenemia, hypofibrinogenemia, and thrombophilia.
Alternative splicing results in two transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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