Thermo Fisher Scientific CCR10 Polyclonal Antibody
CCR10 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC(F), Flow cytometry에 적합. 인간 시료 반응성. Protein G 정제, PBS/BSA buffer에 보관. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:10–1:2,000 |
| Flow Cytometry (Flow) | 1:10–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues 350–362 of human CCR10 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2074266 |
Product Specific Information
- The immunogen sequence is 100% identical in human and mouse.
- Suggested positive control: A-375 or MCF-7, antigen standard for CCR10 (transient overexpression lysate).
Target Information
Chemokines are small (approximately 8–14 kD), mostly basic, structurally related molecules that regulate leukocyte trafficking through interactions with 7-transmembrane, G protein-coupled receptors. They play key roles in immune system development, homeostasis, and function, and also affect CNS and endothelial cells involved in angiogenesis or angiostasis.
Chemokines are divided into two major subfamilies, CXC and CC, based on the arrangement of conserved cysteine residues. CCR10 is the receptor for CCL27, and CCR10–CCL27 interactions are involved in T cell-mediated skin inflammation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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