Thermo Fisher Scientific Dystrophin Polyclonal Antibody
Dystrophin 단백질 검출용 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF, ELISA에 적합합니다. 인간, 마우스, 랫트 반응성을 가지며 액상 형태로 제공됩니다. 고순도 친화 크로마토그래피 정제, 안정적인 PBS/glycerol buffer 저장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 346–635 of human Dystrophin (NP_0039972) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.48 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805696 |
Product Specific Information
- Positive Samples: Mouse heart
- Cellular Location: Cell junction, Cell membrane, Cytoplasm, Cytoplasmic side, Peripheral membrane protein, cytoskeleton, postsynaptic cell membrane, sarcolemma, synapse
Immunogen sequence:
TALEEVLSWL LSAEDTLQAQ GEISNDVEVV KDQFHTHEGY MMDLTAHQGR VGNILQLGSK LIGTGKLSED EETEVQEQMN LLNSRWECLR VASMEKQSNL HRVLMDLQNQ KLKELNDWLT KTEERTRKME EEPLGPDLED LKRQVQQHKV LQEDLEQEQV RVNSLTHMVV VVDESSGDHA TAALEEQLKV LGDRWANICR WTEDRWVLLQ DILLKWQRLT EEQCLFSAWL SEKEDAVNKI HTTGFKDQNE MLSSLQKLAV LKADLEKKKQ SMGKLYSLKQ DLLSTLKNKS
Target Information
Dystrophin is the 427 kDa protein product of the DMB/BMD gene located on the X chromosome at position Xp21. Western blotting and immunohistochemistry are established methods for detecting abnormalities of dystrophin expression in muscle biopsies. Dystrophin abnormalities are found in nearly all patients with DMD/BMD, though genetic abnormalities may only be detected in up to 65% of cases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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