Thermo Fisher Scientific Mitofilin Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 300-400 of human IMMT (NP_0068302) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Mitofilin,uniProtId:Q16891-1,ncbiNodeId:9606,antigenRange:300-400,antigenLength:758,antigenImageFileName:PA5-89627_Mitofilin_Q16891-1_Rabbit.svg,antigenImageFileNamePDP:PA5-89627_Mitofilin_Q16891-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.64 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2805695

Product Specific Information

Positive Samples: SW480, SW620, H460, HepG2, Mouse spleen, Mouse testis; Cellular Location: Mitochondrion, Mitochondrion inner membrane, Single-pass membrane protein

Immunogen sequence: EELEKMKSVI ENAKKKEVAG AKPHITAAEG KLHNMIVDLD NVVKKVQAAQ SEAKVVSQYH ELVVQARDDF KRELDSITPE VLPGWKGMSV SDLADKLSTD D

Target Information

Mitofilin is a transmembrane protein of the inner mitochondrial membrane and it is associated with a large multimeric protein complex of about 1200 kDa. Mitofilin has critical functions in mitochondrial morphology and mitochondrial fusion and fission, specifically in the formation of tubular cristae and cristae junctions. Abnormal mitochondrial morphology has been implicated in many human diseases such as myopathy, cardiomyopathy, rhabdomyosarcoma and Whartin`s tumor.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.