Thermo Fisher Scientific Lamin A/C Recombinant Superclonal Antibody (9HCLC)

Applications

• Western Blot (WB): 1–2 µg/mL

Product Specifications

Product Specific Information

This antibody is predicted to react with Rabbit, Horse, and Pig.

Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They combine multiple recombinant monoclonal antibodies to provide both the sensitivity of polyclonal antibodies and the specificity of monoclonal antibodies, with the consistency of recombinant production.
These antibodies recognize multiple epitopes, enabling higher detection sensitivity for low-abundance targets. Each lot is produced with a defined mixture of light and heavy chains, ensuring reproducibility and eliminating variability found in traditional polyclonal antibodies.

Note: Formerly called “Recombinant polyclonal antibody”, now rebranded as “Recombinant Superclonal™ antibody”. The product and performance remain unchanged.

Target Information

Lamins are intermediate filament proteins forming a matrix on the inner surface of the nuclear envelope.
Lamins A and C are alternatively spliced products of the LMNA gene. Mutations in LMNA are linked to various disorders including:

• Emery-Dreifuss muscular dystrophy
• Dunnigan-type familial partial lipodystrophy (FPLD)
• Limb-girdle muscular dystrophy (LGMD1B)
• Dilated cardiomyopathy (CMD1A)
• Axonal neuropathy (Charcot-Marie-Tooth disease; CMT2B1)
• Mandibuloacral dysplasia (MAD)

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.