Thermo Fisher Scientific CD59 Monoclonal Antibody (1F5)
CD59 단백질을 검출하는 Thermo Fisher Scientific의 Mouse IgG1 단클론 항체로, 인간 및 마우스 시료에 반응. Flow Cytometry에 최적화되어 있으며, Protein G 정제 및 PBS 버퍼에 보관. 비접합형으로 다양한 형광 표지 형식 선택 가능.
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Thermo Fisher Scientific CD59 Monoclonal Antibody (1F5)
Applications
- Flow Cytometry (Flow)
Tested Dilution: 1 µg/1 million cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1F5 |
| Immunogen | Neuraminidase-treated Human Erythrocytes (Neu-HuE) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1073175 |
Additional Formats
Product Specific Information
- MA1-70058 detects CD59 in human samples.
- Successfully used in flow cytometry procedures.
- Immunogen: Neuraminidase-treated Human Erythrocytes (Neu-HuE).
- Store at 4°C. For long-term storage, aliquot and freeze unused portions at -20°C in single-use volumes. Avoid freeze/thaw cycles.
Target Information
CD59 (Protectin) is a small (18–20 kDa) GPI-anchored protein that inhibits the membrane attack complex (MAC). It regulates complement cascade by preventing cytolytic pore formation in the plasma membrane. CD59 also interacts with CD2, contributing to T-cell costimulation and lymphocyte signal transduction. Mutations in CD59 can lead to deficiency causing hemolytic anemia, thrombosis, and cerebral infarction. Multiple alternatively spliced transcript variants have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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