Thermo Fisher Scientific C5AR1 Monoclonal Antibody (8D6)
인간 C5a 수용체(CD88)를 인식하는 Rat IgG2a 단일클론 항체. Flow cytometry 및 동결 절편 IHC에 적합. Protein G 정제, PBS buffer에 0.02% sodium azide 포함. 단기 4°C, 장기 -20°C 보관. 다양한 형광 표지 형식 선택 가능.
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Applications
Immunohistochemistry (Frozen) (IHC (F))
- Assay-dependent
Flow Cytometry (Flow)
- 1 µg/1 million cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rat / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 8D6 |
| Immunogen | RBL-2H3 (rat basophilic leukemia) transfected cells expressing human C5aR on the cell surface |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1073841 |
Additional Formats
Product Specific Information
MA1-70060 detects C5a receptor in human samples.
It has been successfully used in flow cytometry and immunohistochemistry (frozen sections).
The immunogen is RBL-2H3 (rat basophilic leukemia) transfected cells expressing human C5aR on the cell surface.
Target Information
CD88, also known as C5aR1, is a C5a Anaphylatoxin Receptor that mediates the effects of one of the most potent chemotactic agents known.
C5AR1 has been implicated in asthma, and its expression has been reported in myeloid blood cells, brain, liver, lung, spleen, heart, kidney, and intestinal tract.
CD88 is the receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. Functionally, CD88 stimulates chemotaxis, granule enzyme release, and superoxide anion production.
It is also a component of the classical pathway of the complement cascade and may be involved with tissue injury associated with ischemia or sepsis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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