Thermo Fisher Scientific MFN2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 70-260 of mouse Mitofusin 2 (NP_5734642) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MFN2,uniProtId:Q80U63-1,ncbiNodeId:10090,antigenRange:70-260,antigenLength:757,antigenImageFileName:PA5-89321_MFN2_Q80U63-1_Rabbit.svg,antigenImageFileNamePDP:PA5-89321_MFN2_Q80U63-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.38 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2805491

Product Specific Information

Positive Samples: Mouse brain, Rat brain; Cellular Location: Mitochondrion outer membrane, Multi-pass membrane protein

Immunogen sequence: TTEEQVLDVK GYLSKVRGIS EVLARRHMKV AFFGRTSNGK STVINAMLWD KVLPSGIGHT TNCFLRVGGT DGHEAFLLTE GSEEKKSVKT VNQLAHALHQ DEQLHAGSMV SVMWPNSKCP LLKDDLVLMD SPGIDVTTEL DSWIDKFCLD ADVFVLVANS ESTLMQTEKQ FFHKVSERLS RPNIFILNNR W

Target Information

This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.