Thermo Fisher Scientific FAM161B Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human FAM161B. Recombinant protein control fragment (Product #RP-88870). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:FAM161B,uniProtId:Q96MY7-1,ncbiNodeId:9606,antigenRange:15-151,antigenLength:647,antigenImageFileName:PA5-53931_FAM161B_Q96MY7-1_Rabbit.svg,antigenImageFileNamePDP:PA5-53931_FAM161B_Q96MY7-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.4 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2641292

Product Specific Information

Immunogen sequence: GSRQIFPPES FADTEAGEEL SGDGLVLPRA SKLDEFLSPE EEIDSTSDST GSIYQNLQEL KQKGRWCLLE SLFQSDPESD ENLSEDEEDL ESFFQDKDRG MVQVQCPQAL RCGSTRRCSS LNNLPSNIPR PQTQPPS

Highest antigen sequence identity to the following orthologs: Mouse - 66%, Rat - 67%.

Target Information

FAM161B is a 647 amino acid protein that belongs to the FAM161 family. The gene that encodes FAM161B consists of approximately 16,413 bases and maps to human chromosome 14q24.3. Housing over 700 genes, chromosome 14 comprises nearly 3.5% of the human genome. Chromosome 14 encodes the Presenilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer`s disease. The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder 1-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction. An inversion of the long arm of chromosome 14 is thought to be involved in T-cell chronic lymphocytic leukemia (CLL), a cancer that affects T lymphocytes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.