Thermo Fisher Scientific PTPN7 Polyclonal Antibody
Human PTPN7 단백질에 특이적인 Rabbit Polyclonal Antibody로, IHC(P) 등 다양한 연구용 응용에 적합. 항원 친화 크로마토그래피로 정제되었으며, 0.1 mg/mL 농도의 액상 형태로 제공. 단기 4°C, 장기 -20°C 보관 권장.
- 카탈로그번호
- PA553927
- 판매단위
- pk
카탈로그
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Applications
Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PTPN7 (Product #RP-91566) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2646128 |
Product Specific Information
Immunogen sequence:
LIVMLTQLRE GKEKCVHYWP TEEETYGPFQ IRIQDMKECP EYTVRQLTIQ YQEERRSVKH ILFSAWPDHQ TPESAGPLLR LVAEVEESPE TAAHPGPIVV HCSAGIGRTG CFIATRIGCQ QLKARGEVDI LGIVCQL
Ortholog sequence identity:
- Mouse: 93%
- Rat: 92%
Target Information
The protein encoded by this gene belongs to the protein tyrosine phosphatase (PTP) family, which regulates cellular processes such as growth, differentiation, mitotic cycle, and oncogenic transformation.
PTPN7 is preferentially expressed in various hematopoietic cells and acts as an early response gene in lymphokine-stimulated cells.
Its noncatalytic N-terminus interacts with MAP kinases to suppress their activity and plays a role in T cell antigen receptor signaling via dephosphorylation of MAP kinase pathway-related molecules.
Two alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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