Thermo Fisher Scientific SMARCB1 Polyclonal Antibody
SMARCB1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF에 적합하며 Human, Mouse, Rat 반응성 보유. 항원 친화 크로마토그래피로 정제, PBS/glycerol 저장용액 포함, 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SMARCB1. Recombinant protein control fragment (Product #RP-92346). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2647612 |
Product Specific Information
Immunogen sequence:
EKENSPEKFA LKLCSELGLG GEFVTTIAYS IRGQLSWHQK TYAFSENPLP TVEIAIRNTG DADQWCPLLE TLTDAEMEKK IRDQDRNTRR MRRLANTA
Highest antigen sequence identity to the following orthologs:
- Mouse: 100%
- Rat: 100%
Target Information
The SWI-SNF complex is involved in the activation of transcription via remodeling of nucleosome structure in an ATP-dependent manner. Brm (SNF2α) and Brg-1 (SNF2β) are the ATPase subunits of the mammalian SWI-SNF complex. Brm, Brg-1, Ini1 (SNF5), BAF155 (SRG3), and BAF170 form the functional core of the SWI-SNF complex. Addition of Ini1, BAF155, and BAF170 to Brg-1 increases remodeling activity. Other subunits play regulatory roles. hSNF2L and hSNF2H are homologs of Drosophila ISWI, an ATPase present in chromatin remodeling complexes such as NURF.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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