Thermo Fisher Scientific HSP60 Polyclonal Antibody
HSP60 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC, IP 등 다양한 응용에 사용 가능. 미토콘드리아 단백질 접힘 및 조립 연구에 적합하며, 고순도 액상 형태로 제공. 연구용 전용 시약.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
| Immunoprecipitation (IP) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 27–240 of human Hsp60 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.79 mg/mL |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804235 |
Product Specific Information
Immunogen sequence:
AKDVKFGADA RALMLQGVDL LADAVAVTMG PKGRTVIIEQ SWGSPKVTKD GVTVAKSIDL KDKYKNIGAK LVQDVANNTN EEAGDGTTTA TVLARSIAKE GFEKISKGAN PVEIRRGVML AVDAVIAELK KQSKPVTTPE EIAQVATISA NGDKEIGNII SDAMKKVGRK GVITVKDGKT LNDELEIIEG MKFDRGYISP YFINTSKGQK CEFQ
Positive Samples: HeLa, Jurkat, K-562, Mouse kidney, Mouse liver, Mouse thymus, Rat heart
Cellular Location: Mitochondrion matrix
Target Information
This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. It is essential for the folding and assembly of newly imported proteins in the mitochondria. The gene is adjacent to a related family member, with the intergenic region functioning as a bidirectional promoter. Several pseudogenes are associated with this gene. Two transcript variants encoding the same protein have been identified. Mutations are linked to autosomal recessive spastic paraplegia 13.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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