Thermo Fisher Scientific PLP1 Monoclonal Antibody (plpc1)
PLP1 단백질을 인식하는 Mouse Monoclonal Antibody로 다양한 포유류 종에 반응. WB, IHC, ICC 등 다중 응용 가능. 단백질 G로 정제된 고순도 항체로 1 mg/mL 농도. 연구용으로만 사용.
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 1 publication |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | - |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:100 | View 1 publication |
| Flow Cytometry (Flow) | Assay-dependent | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Bovine, Dog, Human, Mouse, Non-human primate, Rat |
| Published Species | Mouse, Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | plpc1 |
| Immunogen | Synthetic peptide GRGTKF corresponding to C terminal region of myelin proteolipid protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | <0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2299793 |
Product Specific Information
Predicted to react with all mammals based on sequence homology.
Mouse anti-myelin proteolipid protein antibody, clone plpc1 recognizes myelin proteolipid protein (PLP) in many mammalian species (Stoffel et al. 1985).
Target Information
PLP1 is a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system.
It plays roles in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival.
Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2.
Alternatively spliced transcript variants encoding distinct isoforms or having different 5` UTRs have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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