Thermo Fisher Scientific BCAT1 Monoclonal Antibody (1F8)
BCAT1 단백질을 표적으로 하는 Mouse IgG2a 단클론 항체로, Western Blot 및 ELISA에 최적화됨. Human 시료에 반응하며, PBS buffer에 보존된 액상 형태. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 1 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1F8 |
| Immunogen | BCAT1 (AAH33864, 1–320 a.a.) full-length recombinant protein with GST tag (MW of GST tag: 26 KDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MDCSNGCSAE CTGEGGSKEV VGTFKAKDLI VTPATILKEK PDPNNLVFGT VFTDHMLTVE WSSEFGWEKP HIKPLQNLSL HPGSSALHYA VELFEGLKAF RGVDNKIRLF QPNLNMDRMY RSAVRATLPV FDKEELLECI QQLVKLDQEW VPYSTSASLY IRPTFIGTEP SLGVKKPTKA LLFVLLSPVG PYFSSGTFNP VSLWANPKYV RAWKGGTGDC KMGGNYGSSL FAQCEAVDNG CQQVLWLYGE DHQITEVGTM NLFLYWINED GEEELATPPL DGIILPGVTR RCILDLAHQW DTELSLFSIN LPDFLQFIYF
Target Information
This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase.
This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth.
Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia.
As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders.
Alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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