Thermo Fisher Scientific BCL2L1 Polyclonal Antibody, MaxPab
인간 BCL2L1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot, ICC/IF, PLA 등 다양한 응용에 사용 가능. PBS 기반 액상 형태로 보존제 없음. -20°C에서 보관하며 연구용으로만 사용.
- 카탈로그번호
- H00000598-D01P
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 10 µg/mL
in situ PLA (PLA)
- Tested Dilution: 1:1200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | BCL2L1 (NP_612815.1, 1–233 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MSQSNRELVV DFLSYKLSQK GYSWSQFSDV EENRTEAPEG TESEMETPSA INGNPSWHLA DSPAVNGATG HSSSLDAREV IPMAAVKQAL REAGDEFELR YRRAFSDLTS QLHITPGTAY QSFEQVVNEL FRDGVNWGRI VAFFSFGGAL CVESVDKEMQ VLVSRIAAWM ATYLNDHLEP WIQENGGWDT FVELYGNNAA AESRKGQERF NRWFLTGMTV AGVVLLGSLF SRK
Target Information
The protein encoded by the BCL-X (BCL2L1) gene belongs to the BCL-2 protein family.
Members of this family form hetero- or homodimers and act as anti- or pro-apoptotic regulators involved in various cellular activities.
These proteins are located at the outer mitochondrial membrane and regulate VDAC opening, which controls mitochondrial membrane potential, reactive oxygen species production, and cytochrome C release — all key factors in apoptosis.
Alternative splicing produces multiple transcript variants encoding two isoforms:
- The longer isoform acts as an apoptotic inhibitor.
- The shorter isoform acts as an apoptotic activator.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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