Thermo Fisher Scientific BAK1 Monoclonal Antibody (1E4)
Human BAK1 단백질을 인식하는 Mouse IgM 단클론 항체로, ELISA 및 Immunoprecipitation에 사용 가능. 액상 형태로 제공되며 보존제 무첨가. -20°C에서 보관하며 동결·해동 반복을 피해야 함. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| ELISA (ELISA) | 10 µg/mL |
| Immunoprecipitation (IP) | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgM, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1E4 |
| Immunogen | BAK1 (AAH04431, 100 a.a. ~ 211 a.a) partial recombinant protein with GST tag. MW of GST tag alone: 26 kDa |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
LQPTAENAYE YFTKIATSLF ESGINWGRVV ALLGFGYRLA LHVYQHGLTG FLGQVTRFVV DFMLHHCIAR WIAQRGGWVA ALNLGNGPIL NVLVVLGVVL LGQFVVRRFF KS
Target Information
The protein encoded by this gene belongs to the BCL2 protein family. Members of this family form oligomers or heterodimers and act as anti- or pro-apoptotic regulators involved in various cellular activities. This protein localizes to mitochondria and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, leading to loss of membrane potential and release of cytochrome c. It also interacts with the tumor suppressor P53 after exposure to cell stress.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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