Thermo Fisher Scientific BAK1 Monoclonal Antibody (1E4)

Applications

Tested Dilution

Publications

ELISA (ELISA)

10 µg/mL

-

Immunoprecipitation (IP)

10 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgM, kappa

Class

Monoclonal

Type

Antibody

Clone

1E4

Immunogen

BAK1 (AAH04431, 100 a.a. approximately 211 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:BAK,uniProtId:Q16611-1,ncbiNodeId:9606,antigenRange:100-211,antigenLength:211,antigenImageFileName:H00000578-M01A_BAK_Q16611-1_House_mouse.svg,antigenImageFileNamePDP:H00000578-M01A_BAK_Q16611-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Storage buffer

ascites

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: LQPTAENAYE YFTKIATSLF ESGINWGRVV ALLGFGYRLA LHVYQHGLTG FLGQVTRFVV DFMLHHCIAR WIAQRGGWVA ALNLGNGPIL NVLVVLGVVL LGQFVVRRFF KS

Target Information

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.