Thermo Fisher Scientific MPP10 Polyclonal Antibody
Thermo Fisher Scientific의 MPP10 폴리클로날 항체로, 인간 MPP10 단백질을 인식합니다. Western blot에 최적화되어 있으며, 친화 크로마토그래피로 정제된 액상 항체입니다. PBS/글리세롤 완충액에 보관되며 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MPHOSPH10 (Accession O00566), corresponding to amino acid residues V543–E593 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900223 |
Product Specific Information
Antibody detects endogenous levels of total MPHOSPH10.
Target Information
MPP10 (M-phase phosphoprotein 10), also known as MPHOSPH10, is a 681 amino acid protein localized to the fibrillar region of the nucleolus. It is phosphorylated during the M phase of the cell cycle and functions as a component of the 60–80S U3 small nucleolar ribonucleoprotein (U3 snoRNP) complex, essential for early pre-18S rRNA processing. MPP10 forms a heterotrimeric complex with IMP-3 and IMP-4, facilitating its nucleolar association. The MPP10 gene is located on human chromosome 2, which contains over 500 genes. Mutations in genes on this chromosome are linked to Phelan-McDermid syndrome, Neurofibromatosis type 2, autism, and schizophrenia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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