Thermo Fisher Scientific CD200R Polyclonal Antibody
Human CD200R1 인식용 Rabbit Polyclonal Antibody로서 Western blot 및 Immunocytochemistry에 적합. 합성 펩타이드 면역원 기반으로 제작되었으며, 액상 형태로 1 mg/mL 농도. PBS + 50% glycerol 보존, -20°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CD200R1 (Accession Q8TD46), corresponding to amino acid residues L250–P300 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900222 |
Product Specific Information
Antibody detects endogenous levels of total MOX2R.
Target Information
CD200R (OX2R) is a receptor for the OX-2 membrane glycoprotein. Both receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains. CD200R is restricted to myeloid lineage cell surfaces, and their interaction may act as a myeloid downregulatory signal.
In mouse, CD200R is expressed mainly by peripheral blood monocytes and neutrophils, as well as other leukocytes including T-lymphocytes and mast cells. Studies suggest that CD200R may control myeloid function in a tissue-specific manner.
Alternative splicing of CD200R results in multiple transcript variants. Diseases associated with CD200R dysfunction include primary hypertrophic osteoarthropathy.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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