Thermo Fisher Scientific PEX3 Polyclonal Antibody
PEX3 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF에 적합합니다. 인간, 생쥐, 랫드 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 1 mg/mL 액상 형태로 제공되며, 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:1,000 | View 1 publication |
| Immunohistochemistry (IHC) | – | View 1 publication |
| Immunocytochemistry (ICC/IF) | – | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 53–98 of human Peroxin 3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553865 |
Product Specific Information
This antibody detects endogenous PEX3 protein at a molecular weight of approximately 42 kDa.
Purity is greater than 95% as determined by SDS-PAGE.
Target Information
Peroxin 3 (PEX3), also known as peroxisomal biogenesis factor 3 or TRG18, is a 373-amino-acid multi-pass membrane protein localized to peroxisomes and a member of the Peroxin family.
PEX3 interacts with Peroxin 19 and plays a critical role in peroxisome biosynthesis, membrane vesicle assembly, and maintenance of peroxisomal integrity.
It acts as a docking factor for Peroxin 19 and is essential for the import of peroxisomal proteins.
Mutations in the PEX3 gene cause peroxisome biogenesis disorder complementation group 12 (PBD-CG12) and Zellweger syndrome (ZwS), both resulting from defective peroxisomal protein import.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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