Thermo Fisher Scientific SLC15A1 Polyclonal Antibody
SLC15A1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 최적화되어 있습니다. Human, Mouse, Rat 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 1 mg/mL 액상 형태로 제공되며, 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:1,000 | View 2 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 269–314 of human SLC15A1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553863 |
Product Specific Information
- Detects endogenous SLC15A1 protein at a molecular weight of approximately 78 kDa.
- Purity is greater than 95% as determined by SDS-PAGE.
Target Information
The proton-coupled peptide transporter (PEPT) in the mammalian small intestine is responsible for absorbing small peptides from dietary protein digestion.
PEPT1 (SLC15A1) is a hydrogen ion/peptide cotransporter that transports dipeptides and tripeptides, but not free amino acids or peptides longer than three residues.
Its activity depends on proton binding and an inside-negative membrane potential.
PEPT1 is a 708-amino-acid protein with 12 predicted membrane-spanning domains and is expressed in Caco-2 cells.
It plays important roles in nutritional and pharmacological therapies.
The mammalian kidney expresses a related transporter, PEPT2, which facilitates absorption of small peptides and peptide-like drugs such as beta-lactam antibiotics from the tubular filtrate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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