Thermo Fisher Scientific HBB Monoclonal Antibody (7B12)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

3 µg/mL

-

ELISA (ELISA)

0.1 ng/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

7B12

Immunogen

HBB (AAH07075, 38 a.a. approximately 147 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:HBB,uniProtId:P68871-1,ncbiNodeId:9606,antigenRange:38-147,antigenLength:147,antigenImageFileName:H00003043-M02_HBB_P68871-1_House_mouse.svg,antigenImageFileNamePDP:H00003043-M02_HBB_P68871-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: WTQRFFESFG DLSTPDAVMG NPKVKAHGKK VLGAFSDGLA HLDNLKGTFA TLSELHCDKL HVDPENFRLL GNVLVCVLAH HFGKEFTPPV QAAYQKVVAG VANALPHKYH

Target Information

The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia. The order of the genes in the beta-globin cluster is 5-epsilon-gamma-G-gamma-A-delta-beta-3.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.