Thermo Fisher Scientific HBB Monoclonal Antibody (7B12)
HBB 단백질을 인식하는 마우스 모노클로날 항체로, Western blot, IHC, ELISA 등에 사용 가능. 인간 시료 반응성. 친화 크로마토그래피로 정제된 액상 형태이며, PBS 버퍼에 보존제 없이 제공됨. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3 µg/mL |
| ELISA | 0.1 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 7B12 |
| Immunogen | HBB (AAH07075, 38 a.a. ~147 a.a.) partial recombinant protein with GST tag. MW of GST tag alone is 26 kDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
WTQRFFESFG DLSTPDAVMG NPKVKAHGKK VLGAFSDGLA HLDNLKGTFA TLSELHCDKL HVDPENFRLL GNVLVCVLAH HFGKEFTPPV QAAYQKVVAG VANALPHKYH
Target Information
The alpha (HBA) and beta (HBB) loci determine the structure of the two types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains.
Mutant beta globin causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin cause beta-plus-thalassemia.
The order of the genes in the beta-globin cluster is 5′-epsilon-gamma-G-gamma-A-delta-beta-3′.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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