Thermo Fisher Scientific Carboxypeptidase B2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Protein corresonding to Human Carboxypeptidase B2. Recombinant protein control fragment (Product #RP-102322). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Carboxypeptidase B2,uniProtId:Q96IY4-1,ncbiNodeId:9606,antigenRange:27-170,antigenLength:423,antigenImageFileName:PA5-110680_Carboxypeptidase_B2_Q96IY4-1_Rabbit.svg,antigenImageFileNamePDP:PA5-110680_Carboxypeptidase_B2_Q96IY4-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2856091

Product Specific Information

Immunogen sequence: QVLAALPRTS RQVQVLQNLT TTYEIVLWQP VTADLIVKKK QVHFFVNASD VDNVKAHLNV SGIPCSVLLA DVEDLIQQQI SNDTVSPRAS ASYYEQYHSL NEIYSWIEFI TERHPDMLTK IHIGSSFEKY PLYVLKVSGK EQAA

Target Information

Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). CPB2 is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for its gene and its promoter region.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.