Thermo Fisher Scientific Carboxypeptidase B2 Polyclonal Antibody
Human Carboxypeptidase B2를 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 검증됨. 항원 친화 크로마토그래피로 정제된 액상 형태이며, PBS/glycerol 버퍼에 보존. 연구용으로만 사용 가능.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein corresponding to Human Carboxypeptidase B2. Recombinant protein control fragment (Product #RP-102322) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2856091 |
Product Specific Information
Immunogen sequence:
QVLAALPRTS RQVQVLQNLT TTYEIVLWQP VTADLIVKKK QVHFFVNASD VDNVKAHLNV SGIPCSVLLA DVEDLIQQQI SNDTVSPRAS ASYYEQYHSL NEIYSWIEFI TERHPDMLTK IHIGSSFEKY PLYVLKVSGK EQAA
Target Information
Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). CPB2 is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for its gene and its promoter region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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