Thermo Fisher Scientific PEX5 Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Product Specific Information

Immunogen sequence:
WQYLGTTQAE NEQELLAISA LRRCLELKPD NQTALMALAV SFTNESLQRQ ACETLRDWLR YTPAYAHLVT PAEEGAGGAG LGPSKRILGS LLSDSLFLEV KELFLAAVRL DPTSIDPDVQ CGLGVLFNLS GEYDKAVDCF TAALSVRPND YLLWNKLGAT LANGNQSEEA VAAYRRALEL QPGYIRSRYN LGISCINLGA HREAVEHFLE ALNMQRKSRG PRGEGGAMSE NIWSTLRLAL SMLGQSDAYG AADARDLSTL LTMFGLPQ

Positive Samples:
U-251MG, HepG2, 293T, HeLa, Mouse brain, Mouse kidney, Mouse liver

Cellular Location:
Cytoplasm, Peripheral membrane protein, Peroxisome membrane

Target Information

The PEX5 gene product binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays a key role in peroxisomal protein import. Peroxins (PEXs) are essential for peroxisome assembly.
Mutations in this gene are associated with peroxisome biogenesis disorders (PBDs), including neonatal adrenoleukodystrophy (NALD), Zellweger syndrome (ZWS), and infantile Refsum disease (IRD).
Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

⚠ WARNING:
This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.