Thermo Fisher Scientific PEX5 Polyclonal Antibody
PEX5 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, ICC/IF, ELISA에 사용 가능. Human, Mouse, Rat 시료에 반응하며, PBS/glycerol buffer에 보관. Peroxisome 관련 단백질 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 364–631 of human PEX5 (NP_0003102) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.13 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20 °C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805015 |
Product Specific Information
Immunogen sequence:
WQYLGTTQAE NEQELLAISA LRRCLELKPD NQTALMALAV SFTNESLQRQ ACETLRDWLR YTPAYAHLVT PAEEGAGGAG LGPSKRILGS LLSDSLFLEV KELFLAAVRL DPTSIDPDVQ CGLGVLFNLS GEYDKAVDCF TAALSVRPND YLLWNKLGAT LANGNQSEEA VAAYRRALEL QPGYIRSRYN LGISCINLGA HREAVEHFLE ALNMQRKSRG PRGEGGAMSE NIWSTLRLAL SMLGQSDAYG AADARDLSTL LTMFGLPQ
Positive Samples:
U-251MG, HepG2, 293T, HeLa, Mouse brain, Mouse kidney, Mouse liver
Cellular Location:
Cytoplasm, Peripheral membrane protein, Peroxisome membrane
Target Information
The PEX5 gene product binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays a key role in peroxisomal protein import. Peroxins (PEXs) are essential for peroxisome assembly.
Mutations in this gene are associated with peroxisome biogenesis disorders (PBDs), including neonatal adrenoleukodystrophy (NALD), Zellweger syndrome (ZWS), and infantile Refsum disease (IRD).
Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
⚠ WARNING:
This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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