Thermo Fisher Scientific PCDH15 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

2 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

5-15 µg/mL

-

Immunocytochemistry (ICC/IF)

5-15 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Sheep / IgG

Class

Polyclonal

Type

Antibody

Immunogen

CHO-derived recombinant human Protocadherin-15 Gln27-Ala1376 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PCDH15,uniProtId:Q96QU1-1,ncbiNodeId:9606,antigenRange:27-1376,antigenLength:1955,antigenImageFileName:PA5-47865_PCDH15_Q96QU1-1_Sheep.svg,antigenImageFileNamePDP:PA5-47865_PCDH15_Q96QU1-1_Sheep_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS with 5% trehalose

Contains

No Preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2605929

Product Specific Information

In direct ELISAs, less than 1% cross-reactivity with recombinant human (rh) Protocadherin-1, rhProtocadherin-8, and rhProtocadherin-10 is observed.

Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.

Target Information

PCDH15 is a member of the cadherin superfamily. Family members encode integral membrane proteins that mediate calcium-dependent cell-cell adhesion. PCDH15 consists of a signal peptide, 11 extracellular calcium-binding domains, a transmembrane domain and a unique cytoplasmic domain. It plays an essential role in maintenance of normal retinal and cochlear function. Mutations in this gene have been associated with hearing loss, which is consistent with its location at the Usher syndrome type 1F (USH1F) critical region on chromosome 10.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.