Thermo Fisher Scientific PCDH15 Polyclonal Antibody
PCDH15 단백질을 인식하는 Thermo Fisher Scientific의 Sheep 유래 Polyclonal 항체. Western blot, IHC, ICC/IF에 사용 가능. 인간 시료 반응성. 항원 친화 크로마토그래피로 정제되었으며, 동결건조 형태로 제공됨. 연구용 전용 제품.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–15 µg/mL |
| Immunocytochemistry (ICC/IF) | 5–15 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CHO-derived recombinant human Protocadherin-15 (Gln27–Ala1376) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2605929 |
Product Specific Information
- In direct ELISAs, less than 1% cross-reactivity with recombinant human Protocadherin-1, Protocadherin-8, and Protocadherin-10 is observed.
- Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.
Target Information
PCDH15 is a member of the cadherin superfamily. These proteins mediate calcium-dependent cell-cell adhesion and are integral membrane proteins.
PCDH15 contains a signal peptide, 11 extracellular calcium-binding domains, a transmembrane domain, and a unique cytoplasmic domain.
It plays an essential role in maintaining normal retinal and cochlear function.
Mutations in this gene are associated with hearing loss and are linked to the Usher syndrome type 1F (USH1F) critical region on chromosome 10.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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