
Thermo Fisher Scientific IFNGR1 Polyclonal Antibody
Human IFNGR1 단백질을 표적으로 하는 Goat 유래 Polyclonal Antibody로, WB, ICC/IF, Neutralization 실험에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 동결건조 형태로 제공. 인간 IFNGR2와의 교차 반응은 1% 미만.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1 µg/mL |
| Immunocytochemistry (ICC/IF) | 5–15 µg/mL |
| Neutralization (Neu) | 0.5–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human IFN-gamma R1/CD119 (Glu18–Gly245) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609395 |
Product Specific Information
- In direct ELISAs, less than 1% cross-reactivity with recombinant human IFN-gamma R2 is observed.
- Reconstitute at 0.2 mg/mL in sterile PBS.
- Endotoxin level is <0.10 EU per 1 µg of antibody (LAL method).
Target Information
The IFNGR1 gene encodes the ligand-binding chain (alpha) of the gamma interferon receptor.
Human interferon-gamma receptor is a heterodimer consisting of IFNGR1 and IFNGR2.
Genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection.
Defects in IFNGR1 are linked to mendelian susceptibility to mycobacterial disease (familial disseminated atypical mycobacterial infection).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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