Thermo Fisher Scientific KVbeta2 (KCNAB2) Polyclonal Antibody
Thermo Fisher Scientific의 KVbeta2 (KCNAB2) 폴리클로날 항체는 인간 시료에 반응하며, WB 및 IHC에 적합합니다. 합성 펩타이드로부터 유래된 항원으로 제작되었으며, 고순도의 친화 크로마토그래피 정제 항체입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–1.0 µg/mL |
| Immunohistochemistry (IHC) | 1:600 |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-Dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human KCNAB2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2688349 |
Product Specific Information
This target displays homology in the following species:
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%.
Target Information
Kcnab2 is a voltage-gated potassium channel (KV) belonging to the 6-TM family of potassium channels, which also includes the Ca²⁺-activated Slo (7-TM) and SK subfamilies. The alpha-subunits form tetramers containing a single pore-forming region. Kv channels are involved in regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume.
Four sequence-related potassium channel genes — shaker, shaw, shab, and shal — have been identified in Drosophila, each with human homologs.
Kcnab2 encodes one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits.
Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Diseases associated with KCNAB2 include Chromosome 1P36 Deletion Syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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