Thermo Fisher Scientific P2X2 Polyclonal Antibody
P2X2 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot에 적합합니다. 인간 P2X2 중간 영역(aa 90-139)을 면역원으로 사용하였으며, 다양한 종에서 높은 상동성을 보입니다. 액상 형태로 제공되며, -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human P2X2 (aa 90–139) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2691315 |
Product Specific Information
This target displays homology in the following species:
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Target Information
P2rx2 belongs to the ligand-gated ion channel family that opens in response to extracellular ATP. Each receptor is a trimer of subunits (P2X1–7) sharing two transmembrane domains. P2rx2 mediates synaptic transmission between neurons and from neurons to smooth muscle.
It is involved in excitatory postsynaptic responses, neuromuscular junction formation, hearing, taste perception, and peristalsis. In the inner ear, P2rx2 regulates sound transduction, auditory neurotransmission, outer hair cell electromotility, inner ear gap junctions, and K⁺ recycling.
Diseases associated with P2RX2 include Deafness, Autosomal Dominant 41 and DFNA41 Nonsyndromic Hearing Loss and Deafness.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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