Thermo Fisher Scientific GTF2B/ TFIIB (Transcription Factor 2B) Monoclonal Antibody (PCRP-GTF2B-1D1)
Human GTF2B 단백질을 인식하는 Mouse monoclonal antibody로, ELISA, Flow Cytometry, Immunoprecipitation 등 다양한 응용 가능. Recombinant full-length human GTF2B를 면역원으로 사용하며, Protein A/G 정제된 액상 형태. 연구용으로만 사용 가능.
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Thermo Fisher Scientific GTF2B/TFIIB (Transcription Factor 2B) Monoclonal Antibody (PCRP-GTF2B-1D1)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
| ELISA | Assay-dependent |
| Immunoprecipitation (IP) | 1–2 µg/500 µg lysate |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PCRP-GTF2B-1D1 |
| Immunogen | Recombinant full-length human GTF2B protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Ubiquitin is a 76 amino acid highly conserved eukaryotic polypeptide that selectively marks cellular proteins for proteolytic degradation by the 26S proteasome. The process of target selection, covalent attachment, and shuttle to the 26S proteasome regulates concentrations of key cellular proteins by limiting their lifespans. Polyubiquitination is a common feature of this modification. Serial steps for modification include activation of ubiquitin by E1 enzyme, transfer to E2 conjugating enzyme, and covalent linkage to target proteins directly or via E3 ligase. Deubiquitination enzymes reverse this marking. Posttranslational tagging by ubiquitin is involved in numerous cellular processes, including cell cycle, growth, differentiation, apoptosis, signal transduction, DNA repair, transcription regulation, transport, stress response, immune response, and nervous system function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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