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Thermo Fisher Scientific GTF2H2/BTF2/TFIIH Basal Transcription Factor Monoclonal Antibody (PCRP-GTF2H2-1B9)
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Thermo Fisher Scientific GTF2H2/BTF2/TFIIH Basal Transcription Factor Monoclonal Antibody (PCRP-GTF2H2-1B9)

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TFIIH 복합체 구성요소인 GTF2H2 단백질을 인식하는 마우스 단클론 항체로, 인간 시료에 반응합니다. ICC/IF, Flow Cytometry, Peptide Array 등 다양한 응용에 적합합니다. 단백질 A/G로 정제된 액상 형태이며, 보존제가 없습니다.

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pk
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Thermo Fisher Scientific 2966-MSM1-P1ABX GTF2H2/BTF2/TFIIH Basal Transcription Factor Monoclonal Antibody (PCRP-GTF2H2-1B9) 100 ug pk판매 단위 pk
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825,100원VAT 포함 907,610원

Thermo Fisher Scientific · Thermo Fisher Scientific GTF2H2/BTF2/TFIIH Basal Transcription Factor Monoclonal Antibody (PCRP-GTF2H2-1B9)

Applications

Immunocytochemistry (ICC/IF)

  • Tested Dilution: 1–2 µg/mL

Flow Cytometry (Flow)

  • Tested Dilution: 1–2 µg/10^6 cells

Peptide Array (Array)

  • Tested Dilution: Assay-dependent

Product Specifications

항목 내용
Species Reactivity Human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Clone PCRP-GTF2H2-1B9
Immunogen Recombinant full-length human GTF2H2 protein
Conjugate Unconjugated
Form Liquid
Concentration 1 mg/mL
Purification Protein A/G
Storage Buffer PBS, pH 7.4
Contains No preservative
Storage Conditions -20°C or -80°C if preferred
Shipping Conditions Ambient (domestic); Wet ice (international)

Target Information

Initiation of transcription from protein-coding genes in eukaryotes is a complex process requiring RNA polymerase II and basal transcription factors. Binding of TFIID (TBP) to the TATA box initiates formation of a multiprotein complex containing TFIIA, TFIIB, TFIIE, TFIIF, and TFIIH.
TFIIH (also known as BTF2) is a multisubunit transcription/DNA repair factor with several enzymatic activities. The core of TFIIH includes five subunits: p89 (XPB/ERCC3), p62, p52, p44, and p34. Additional subunits include p80 (XPD/ERCC2) and a kinase complex composed of Cdk7, cyclin H, and MAT1. Both p89 and p80 possess ATP-dependent helicase activity, while p62, p52, and p44 are involved in nucleotide excision repair.


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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