Thermo Fisher Scientific GTF2H2/BTF2/TFIIH Basal Transcription Factor Monoclonal Antibody (PCRP-GTF2H2-1B9)
인간 GTF2H2 단백질을 표적으로 하는 단클론 항체로, TFIIH 복합체 연구에 적합합니다. ICC/IF, Flow Cytometry, Peptide Array 등 다양한 응용 가능. 단백질 A/G로 정제된 액상 형태이며, 4°C 보관.
- 카탈로그번호
- 2966-MSM1-P1
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific GTF2H2/BTF2/TFIIH Basal Transcription Factor Monoclonal Antibody (PCRP-GTF2H2-1B9)
Thermo Fisher Scientific GTF2H2/BTF2/TFIIH Basal Transcription Factor Monoclonal Antibody (PCRP-GTF2H2-1B9)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PCRP-GTF2H2-1B9 |
| Immunogen | Recombinant full-length human GTF2H2 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Initiation of transcription from protein-coding genes in eukaryotes requires RNA polymerase II and several basal transcription factors. Binding of TFIID (TBP) to the TATA box initiates formation of a multiprotein complex including TFIIA, TFIIB, TFIIE, TFIIF, and TFIIH.
TFIIH (or BTF2) is a multisubunit transcription/DNA repair factor with multiple enzymatic activities. Its core comprises five subunits: p89 (XPB/ERCC3), p62, p52, p44, and p34. Additional subunits include p80 (XPD/ERCC2) and the ternary kinase complex (Cdk7, cyclin H, MAT1).
Both p89 and p80 exhibit ATP-dependent helicase activity, while p62, p52, and p44 are involved in nucleotide excision repair.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 없음)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.