Thermo Fisher Scientific ALDH3A2 Polyclonal Antibody
인간 ALDH3A2 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 polyclonal 항체. IHC(P)에서 2–4 µg/mL 농도로 사용 가능. 장쇄 알데하이드 산화를 촉매하는 효소 연구에 적합. -20°C 보관, Wet ice 배송.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–4 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-SLKREGANKLRYPP, from the internal region of ALDH3A2 (aa 429–443) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2554444 |
Product Specific Information
- This antibody is predicted to react with dog and cow based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 32,000.
Target Information
Aldh3A2 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. These enzymes play a major role in detoxifying aldehydes generated by alcohol metabolism and lipid peroxidation.
Aldh3A2 catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Mutations in the Aldh3A2 gene cause Sjogren-Larrson syndrome, an inherited neurocutaneous disorder characterized by ichthyosis, mental retardation, and spastic diplegia. The pathogenesis is thought to result from abnormal lipid accumulation or defective eicosanoid metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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