Thermo Fisher Scientific NF-YA Polyclonal Antibody

Applications

Immunohistochemistry (IHC)

• Tested Dilution: 1:100–1:500

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:100–1:500

Product Specifications

Product Specific Information

• Recommended shelf life: 1 year from date of receipt
• Based on 100% sequence identity, this antibody is predicted to react with Rat, Bovine, Dog, Horse, Rabbit, Guinea pig, Pig, Panda, Orangutan, Monkey, Gorilla, Chimpanzee, and Crab-eating macaque

Target Information

The SMN1 gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. The telomeric and centromeric copies of this gene are nearly identical and encode the same protein — survival motor neuron protein. The SMN complex plays a catalytic role in the assembly of small nuclear ribonucleoproteins, the building blocks of the spliceosome. Mutations in the SMN1 gene are known to cause spinal muscular atrophy types 1 and 2.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.