Thermo Fisher Scientific Fibrinogen gamma Polyclonal Antibody
Thermo Fisher Scientific의 Fibrinogen gamma Polyclonal Antibody는 인간 및 마우스 반응성을 가지며, Western blot과 ELISA에 최적화된 고순도 항체입니다. Rabbit IgG 폴리클로날 형태로, PBS와 글리세롤 버퍼에 보관되며 연구용으로 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 50–330 of human FGG (NP_0005002) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.44 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2901653 |
Product Specific Information
- Positive Samples: Mouse liver
- Immunogen sequence:
GIADFLSTYQ TKVDKDLQSL EDILHQVENK TSEVKQLIKA IQLTYNPDES SKPNMIDAAT LKSRKMLEEI MKYEASILTH DSSIRYLQEI YNSNNQKIVN LKEKVAQLEA QCQEPCKDTV QIHDITGKDC QDIANKGAKQ SGLYFIKPLK ANQQFLVYCE IDGSGNGWTV FQKRLDGSVD FKKNWIQYKE GFGHLSPTGT TEFWLGNEKI HLISTQSAIP YALRVELEDW NGRTSTADYA MFKVGPEADK YRLTYAYFAG GDAGDAFDGF DFGDDPSDKF F
Target Information
The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin, which is the most abundant component of blood clots. Various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and act as mitogens for several cell types. Mutations in this gene lead to disorders such as dysfibrinogenemia, hypofibrinogenemia, and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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