Thermo Fisher Scientific HADHB Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

1:10-1:100

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 34-270 of human HADHB (NP_0001741) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:HADHB,uniProtId:P55084-1,ncbiNodeId:9606,antigenRange:34-270,antigenLength:474,antigenImageFileName:PA5-117024_HADHB_P55084-1_Rabbit.svg,antigenImageFileNamePDP:PA5-117024_HADHB_P55084-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.34 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2901654

Product Specific Information

Positive Samples: BT-474, SW480, HepG2, 293T, Jurkat, Mouse liver, Mouse kidney, Mouse heart, Rat liver

Immunogen sequence: AAPAVQTKTK KTLAKPNIRN VVVVDGVRTP FLLSGTSYKD LMPHDLARAA LTGLLHRTSV PKEVVDYIIF GTVIQEVKTS NVAREAALGA GFSDKTPAHT VTMACISANQ AMTTGVGLIA SGQCDVIVAG GVELMSDVPI RHSRKMRKLM LDLNKAKSMG QRLSLISKFR FNFLAPELPA VSEFSTSETM GHSADRLAAA FAVSRLEQDE YALRSHSLAK KAQDEGLLSD VVPFKVP

Target Information

This gene encodes the beta subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the beta subunit catalyzing the 3-ketoacyl-CoA thiolase activity. The encoded protein can also bind RNA and decreases the stability of some mRNAs. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation. Mutations in this gene result in trifunctional protein deficiency. Alternatively spliced transcript variants encoding different isoforms have been described.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.