Thermo Fisher Scientific AAAS Monoclonal Antibody (OTI7H7), TrueMAB
AAAS 단백질을 인식하는 Mouse 단일클론 항체로, Western blot과 IHC(P)에서 검증됨. Human, Mouse, Rat에서 반응하며, 비접합 형태로 제공. 동결건조 상태로 공급되며 -20°C에서 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7H7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 322–546 of human AAAS produced in E. coli. Target family: Aladin (UniProt ID: Q9NRG9-1) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, it is recommended to perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The AAAS gene encodes a WD-repeat family protein involved in the normal development of the peripheral and central nervous systems. This protein is a component of the nuclear pore complex, anchored by NDC1.
Mutations in this gene cause achalasia-addisonianism-alacrima syndrome (AAAS), also known as triple-A syndrome or Allgrove syndrome. Two transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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